Biology (term coined by Lamarck & Treviranus, 1802) is the science of living organisms. Aristotle — the Father of Biology — laid its foundations. For SSC exams, biology questions focus on human body systems, nutrition & deficiency diseases, genetics, diseases & their pathogens, and ecology. This note covers every high-yield fact the exam has ever asked.
THE CELL
The Cell Theory was proposed by Schleiden & Schwann (1838): every living organism is made of one or more cells, and cells arise only from pre-existing cells. Cells are prokaryotic (no true nucleus — bacteria, mycoplasma, blue-green algae) or eukaryotic (nucleus + membrane-bound organelles — plants, animals, fungi). Think of it like: prokaryote = budget phone (no cover), eukaryote = flagship phone (fully covered).
| Feature | Plant Cell | Animal Cell |
|---|---|---|
| Cell wall | Present (cellulose) | Absent |
| Chloroplast | Present | Absent |
| Central vacuole | Large single vacuole | Small or absent |
| Centriole | Absent (usually) | Present |
| Shape | Fixed, rectangular | Irregular, flexible |
| Lysosomes | Rare | Common (suicidal bags) |
| Organelle | Function | Found In |
|---|---|---|
| Mitochondria | ATP production — powerhouse of cell | Both (more in animal) |
| Chloroplast | Photosynthesis (contains chlorophyll) | Plant only |
| Ribosome | Protein synthesis | Both |
| Nucleus | Controls cell activities; contains DNA | Eukaryotes only |
| Endoplasmic Reticulum (ER) | Transport network; rough ER has ribosomes | Both |
| Golgi Body | Packaging & secretion of proteins | Both |
| Lysosome | Digests waste — 'suicidal bag' | Mainly animal |
| Vacuole | Storage (large in plants, turgor pressure) | Both |
| Cell membrane | Controls entry/exit (selectively permeable) | Both |
| Centrosome / Centriole | Cell division | Animal only |
CLASSIFICATION OF LIVING ORGANISMS
Carolus Linnaeus (18th century) introduced binomial nomenclature — every organism gets a two-part Latin name (genus + species). R.H. Whittaker (1969) classified all life into five kingdoms. The hierarchy from broadest to narrowest is: Kingdom → Phylum → Class → Order → Family → Genus → Species (mnemonic: King Philip Came Over For Good Soup).
- Bacteria (E. coli, Salmonella)
- Mycoplasma (smallest cells)
- Blue-green algae (Cyanobacteria)
- No true nucleus
- Protozoa: Amoeba, Paramecium, Plasmodium
- Algae: Euglena, Diatoms
- Slime moulds
- Mushrooms (Agaricus)
- Yeast (Saccharomyces)
- Moulds: Penicillium, Aspergillus
- No chlorophyll; absorb nutrients
- Mosses (Bryophyta)
- Ferns (Pteridophyta)
- Conifers (Gymnosperms)
- Flowering plants (Angiosperms — rice, mango, rose)
- Porifera (sponges)
- Annelida (earthworm)
- Arthropoda (insects, crabs)
- Chordata: fish, frog, reptile, birds, mammals
HUMAN BODY SYSTEMS
The human body has 11 organ systems. Each system has a core structure, a key function, and landmark SSC facts. SSC loves asking about the smallest/largest bones, blood groups, and specific enzymes — so memorize those numbers cold.
Skeletal System
The human skeleton has 206 bones in adults (infants have ~300; many fuse during growth). Bones provide structure, protect organs, store calcium/phosphorus, and produce blood cells in the red bone marrow. Joints connect bones — ball-and-socket (hip, shoulder), hinge (knee, elbow), pivot (neck), etc.
| Fact | Detail |
|---|---|
| Total bones (adult) | 206 |
| Bones in infant | ~300 (fuse over time) |
| Smallest bone | Stapes (stirrup) — in the middle ear |
| Largest bone | Femur (thigh bone) |
| Largest vertebra | Lumbar vertebra |
| Bone marrow function | Produces RBC, WBC, and platelets (haematopoiesis) |
| Hardest substance in body | Enamel (tooth) |
| Bones in skull | 22 (8 cranial + 14 facial) |
| Ribs | 24 (12 pairs); last 2 pairs = floating ribs |
| Vertebral column | 33 vertebrae (5 regions: cervical-7, thoracic-12, lumbar-5, sacral-5, coccygeal-4) |
Muscular System
The body has over 600 muscles. Muscles are the only tissue that can contract. The largest muscle is the Gluteus Maximus (buttock); the smallest is the Stapedius (attached to stapes in ear).
| Type | Location | Control | Features |
|---|---|---|---|
| Skeletal (striated) | Arms, legs, back | Voluntary (conscious control) | Multinucleated; fast, powerful; tires quickly |
| Cardiac | Heart only | Involuntary (auto-rhythmic) | Branched, intercalated discs; never fatigues |
| Smooth (visceral) | Stomach, intestines, blood vessels | Involuntary | Spindle-shaped; slow, sustained contractions |
Circulatory System
The heart is a myogenic organ (self-contracts) with 4 chambers. The SA node (sino-atrial node) in the right atrium acts as the pacemaker — it initiates each heartbeat. Normal blood pressure = 120/80 mmHg (systole/diastole). An adult has 5–6 litres of blood.
| Component | Description | Key Fact |
|---|---|---|
| RBC (Erythrocytes) | Red blood cells; carry O₂ via haemoglobin | No nucleus in mature RBC; lifespan = 120 days; produced in bone marrow |
| WBC (Leukocytes) | White blood cells; fight infection | 5 types: Neutrophils (65%, bacteria), Lymphocytes (26%, antibodies), Monocytes (policeman of blood), Eosinophils, Basophils |
| Platelets (Thrombocytes) | Clotting; produced in bone marrow | Lifespan = 8–10 days; count: 1.5–4 lakh/mm³ |
| Plasma | Liquid part (~60% of blood) | 90–92% water; carries proteins (albumin, fibrinogen), hormones, nutrients |
| Blood Group | Antigen on RBC | Antibody in Plasma | Can Donate To | Can Receive From |
|---|---|---|---|---|
| A | A antigen | Anti-B | A, AB | O, A |
| B | B antigen | Anti-A | B, AB | O, B |
| AB | A and B | None (no antibodies) | AB only | O, A, B, AB (Universal Recipient) |
| O | None | Anti-A and Anti-B | O, A, B, AB (Universal Donor) | O only |
Respiratory System
Respiration converts food (glucose) into energy using oxygen: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O + ATP (energy). Aerobic respiration (with O₂) happens in mitochondria. Anaerobic respiration (without O₂) produces lactic acid in muscles (causing cramps). The normal breathing rate is 16–20 breaths/minute; tidal volume = 500 mL per breath.
| Respiratory Organ | Animal |
|---|---|
| Lungs | Reptiles, mammals, birds (+ air sacs) |
| Gills | Fish, tadpoles, prawns |
| Skin | Frog, earthworm, leeches |
| Tracheae | Insects, centipedes, millipedes |
| Book lungs | Spider, scorpion |
| Body surface | Protozoans, sponges (porifera) |
Digestive System
Digestion converts complex food molecules into simple absorbable units via hydrolysis (enzyme-driven). The journey: Mouth → Oesophagus → Stomach → Small Intestine (duodenum → jejunum → ileum) → Large Intestine → Rectum → Anus. The small intestine (6–7 m long) is the chief site of digestion and absorption. The large intestine (1.5 m) absorbs water and forms faeces.
| Enzyme | Source / Site | Substrate | Product |
|---|---|---|---|
| Salivary amylase (ptyalin) | Salivary glands → Mouth | Starch (polysaccharides) | Disaccharides (maltose) |
| Pepsin | Stomach mucosa → Stomach | Proteins | Peptide fragments |
| Pancreatic amylase | Pancreas → Small intestine | Starch | Disaccharides |
| Trypsin & Chymotrypsin | Pancreas → Small intestine | Proteins | Peptide fragments |
| Lipase | Pancreas → Small intestine | Triglycerides (fats) | Fatty acids + glycerol |
| Intestinal disaccharidases | Small intestine | Disaccharides | Monosaccharides (glucose) |
| Nucleases | Pancreas & intestine | DNA & RNA | Nucleotides |
Nervous System
The nervous system has two divisions: CNS (brain + spinal cord) and PNS (all other nerves). The basic unit is the neuron (nerve cell) — the longest cell in the body. The brain has three major regions. Reflexes are involuntary responses controlled by the spinal cord, not the brain — that's why you pull your hand from fire before 'feeling' the pain.
| Brain Region | Function |
|---|---|
| Cerebrum (forebrain) | Thinking, intelligence, memory, consciousness, speech, voluntary actions |
| Hypothalamus | Thermostat of body; controls hunger, thirst, sleep, emotions, body temperature |
| Cerebellum (hindbrain) | Balance, coordination of muscle movement, posture |
| Medulla oblongata (hindbrain) | Controls heart rate, breathing, blood pressure, reflex centre — vital for survival |
| Midbrain | Reflex centre for visual and auditory responses |
Endocrine System (Hormones)
Endocrine glands are ductless — they secrete hormones directly into the bloodstream. The pituitary gland (smallest endocrine gland, at base of brain) is called the master gland because it controls all other endocrine glands. Hormones are chemical messengers that regulate metabolism, growth, reproduction, and responses to stress.
| Gland | Hormone | Function | Deficiency / Excess |
|---|---|---|---|
| Pituitary (master gland) | Growth Hormone (GH) | Controls body growth | Deficiency → Dwarfism; Excess → Gigantism/Acromegaly |
| Pituitary | ADH (Vasopressin) | Water reabsorption in kidneys | Deficiency → Diabetes insipidus |
| Thyroid | Thyroxine (T4) | Regulates metabolism, growth | Deficiency → Hypothyroidism, Goitre, Cretinism (in children); Excess → Hyperthyroidism |
| Parathyroid | PTH (Parathormone) | Regulates calcium & phosphorus | Deficiency → Muscle cramps (tetany) |
| Adrenal cortex | Cortisol, Aldosterone | Stress response; salt/water balance | Deficiency → Addison's disease |
| Adrenal medulla | Adrenaline (Epinephrine) | Fight-or-flight response; increases heart rate | — |
| Pancreas (Islets of Langerhans) | Insulin (β cells) | Lowers blood glucose (uptake by cells) | Deficiency → Diabetes mellitus (Type 1) |
| Pancreas | Glucagon (α cells) | Raises blood glucose (glycogen → glucose) | — |
| Testes | Testosterone | Male secondary sexual characteristics | Deficiency → Delayed puberty, reduced fertility |
| Ovaries | Estrogen, Progesterone | Female sexual characteristics, menstrual cycle, pregnancy | Deficiency → Menstrual irregularities, menopause |
| Thymus | Thymosin | Maturation of T-lymphocytes (immunity) | Deficiency → Poor immune response |
| Pineal gland | Melatonin | Regulates sleep-wake cycle (circadian rhythm) | — |
Excretory System
The kidneys maintain the body's fluid and electrolyte balance by filtering blood and producing urine. The nephron is the structural and functional unit of the kidney — each kidney has ~1 million nephrons. Urine is pale yellow due to the pigment urochrome. Normal urine composition: ~95% water, 2.6% urea, 2% salts, 0.3% uric acid. Volume: 1–2 litres/day. pH: ~6.0 (mildly acidic).
| Excretory Organ | Animal |
|---|---|
| Kidneys (nephrons) | Mammals, birds, reptiles |
| Contractile vacuole | Amoeba |
| Flame cells (solenocytes) | Tapeworm, flatworms |
| Nephridia | Earthworm |
| Malpighian tubules | Cockroach, insects |
| Green glands | Prawn |
| Coxal glands | Scorpion |
NUTRITION & DEFICIENCY DISEASES
The human body requires macronutrients (carbohydrates, proteins, fats) for energy and building, and micronutrients (vitamins, minerals) for metabolic processes. Vitamins are either fat-soluble (A, D, E, K — stored in body fat, so excess can be toxic) or water-soluble (B-complex, C — not stored, must be consumed daily). SSC frequently asks: which vitamin deficiency causes which disease.
| Nutrient | Rich Sources | Deficiency Disease / Effect |
|---|---|---|
| Vitamin A (Retinol) | Fish liver oil, carrots, leafy veg | Night blindness (Nyctalopia), dry skin |
| Vitamin B₁ (Thiamine) | Yeast, cereals, pork | Beriberi (nerve damage, muscle weakness) |
| Vitamin B₂ (Riboflavin) | Liver, milk, eggs | Cracked skin, blurred vision |
| Vitamin B₃ (Niacin) | Liver, whole cereals | Pellagra (skin problems, diarrhoea, dementia — 3 Ds) |
| Vitamin B₁₂ (Cyanocobalamin) | Liver, fish, milk (not in plants) | Pernicious anaemia, nerve disorders |
| Vitamin C (Ascorbic acid) | Citrus fruits, amla, peppers | Scurvy (bleeding gums, poor wound healing) |
| Vitamin D (Calciferol) | Sunlight, fish oil, egg yolk | Rickets (children — soft bones), Osteomalacia (adults) |
| Vitamin E (Tocopherol) | Vegetable oils, cereals | Sterility, mild anaemia (rare in humans) |
| Vitamin K (Phylloquinone) | Dark green veg, gut bacteria | Delayed blood clotting, excessive bleeding |
| Iron (Fe) | Meat, spinach, legumes | Anaemia (low haemoglobin) |
| Calcium (Ca) | Milk, dairy, green veg | Osteoporosis, tetany, rickets |
| Iodine (I) | Seafood, iodised salt | Goitre, cretinism (in children) |
| Protein | Pulses, meat, dairy | Kwashiorkor (children — swollen belly); Marasmus (severe wasting) |
| Folic acid (B₁₀) | Green veg, liver, yeast | Neural tube defects in foetus; Anaemia |
GENETICS
Genetics is the study of heredity and variation. Gregor Mendel (1866) — the 'Father of Genetics' — experimented on pea plants (Pisum sativum) and discovered the laws of inheritance. The physical carrier of hereditary information is DNA (Deoxyribonucleic Acid). The double-helix structure of DNA was discovered by Watson & Crick (1953). DNA is organised into chromosomes in the cell nucleus.
- 4 bases: Adenine (A), Guanine (G), Cytosine (C), Thymine (T)
- A pairs with T; G pairs with C (Chargaff's rule)
- RNA uses Uracil (U) instead of Thymine
- Watson & Crick double helix model — 1953
- Segments of DNA that code for proteins
- Located on chromosomes
- Dominant vs Recessive alleles
- Humans: 46 chromosomes (23 pairs)
- 22 pairs autosomes + 1 pair sex chromosomes
- Female: XX | Male: XY
- Sex is determined by father (Y chromosome)
- Law of Segregation: alleles separate during gamete formation
- Law of Independent Assortment: genes on different chromosomes assort independently
- Dominant trait appears in F1; recessive appears in F2 (3:1 ratio)
| Fact | Detail |
|---|---|
| Human chromosomes | 46 (23 pairs) |
| Sex chromosomes | Female = XX; Male = XY |
| Sex determined by | Father (Y chromosome) |
| DNA structure discovered | Watson & Crick, 1953 |
| Mendel's plant | Pea plant (Pisum sativum) |
| Mendel's laws | Law of Segregation + Law of Independent Assortment |
| First cloned mammal | Dolly the sheep (Ian Wilmut, UK, 1996) |
| World's first test tube baby | Louise Joy Brown, UK, 1978 |
| India's first test tube baby | Harsha, Mumbai, 1986 |
| Genetic engineering | Inserting foreign DNA into host DNA (recombinant DNA technology) |
| Bt crops | Contain Bacillus thuringiensis toxin gene; Bt-cotton was first GM crop in India |
DISEASES & PATHOGENS
Diseases are caused by pathogens (infectious agents) or by non-infectious causes (deficiency, genetic, degenerative). Pathogens include viruses (smallest; need host cell — no cure, only vaccines/antivirals), bacteria (treated with antibiotics; Robert Koch discovered cholera & TB bacterium), fungi (treated with antifungals), and parasites (protozoa, helminths — treated with antiparasitics). SSC regularly tests the causal agent, vector, and vaccine for major diseases.
| Disease | Causative Agent | Type | Vector / Transmission | Affected Organ | Vaccine / Treatment |
|---|---|---|---|---|---|
| Malaria | Plasmodium (P. vivax, P. falciparum) | Parasite (Protozoa) | Female Anopheles mosquito | RBC / Liver | Quinine, chloroquine; No routine vaccine (RTS,S approved 2021) |
| Dengue | Dengue virus (Flavivirus) | Virus (RNA) | Aedes aegypti mosquito (day-biting) | Platelets / blood | No specific antiviral; supportive care; platelet count drops |
| Chikungunya | Chikungunya virus (Alphavirus) | Virus (RNA) | Aedes aegypti / albopictus | Joints / muscles | No specific treatment; pain management |
| Tuberculosis (TB) | Mycobacterium tuberculosis | Bacteria | Airborne droplets | Lungs | BCG vaccine; antibiotics (DOTS) |
| Typhoid | Salmonella typhi | Bacteria | Contaminated food/water | Intestines | TAB vaccine; antibiotics |
| Cholera | Vibrio cholerae | Bacteria | Contaminated water | Intestines | ORS; oral cholera vaccine |
| Plague | Yersinia pestis (Pasteurella pestis) | Bacteria | Rat fleas (Xenopsylla cheopis) | Lymph nodes / lungs | Plague vaccine; antibiotics |
| Leprosy | Mycobacterium leprae | Bacteria | Prolonged contact | Skin / nerves | MDT (multidrug therapy); BCG offers partial protection |
| Polio | Poliovirus | Virus | Faecal-oral route | Motor neurons (spinal cord) | Salk IPV vaccine (1954); Sabin OPV (oral, 1955) |
| Rabies | Rhabdovirus | Virus | Animal bite (dog, bat) | Brain / CNS | Pasteur's vaccine (1885); post-exposure prophylaxis |
| AIDS | HIV (Human Immunodeficiency Virus) | Virus (Retrovirus) | Blood, sexual contact, mother-to-child | T-helper cells (CD4+ lymphocytes) | No cure; ARV (antiretroviral therapy) |
| COVID-19 | SARS-CoV-2 (Novel Coronavirus) | Virus (RNA) | Airborne droplets, contact | Respiratory tract / lungs | Multiple vaccines (Covishield, Covaxin, etc.) |
| Kala-azar (Leishmaniasis) | Leishmania donovani | Parasite (Protozoa) | Female Phlebotomus sandfly | Spleen / liver / bone marrow | Miltefosine; amphotericin B |
| Filariasis (Elephantiasis) | Wuchereria bancrofti (roundworm) | Parasite (Nematode) | Culex mosquito | Lymphatic system / legs | DEC (diethylcarbamazine) |
| Chickenpox | Varicella-Zoster virus | Virus | Airborne / contact | Skin / nerves | Varicella vaccine |
| Smallpox (Eradicated) | Variola virus | Virus | Airborne / contact | Skin | Edward Jenner's cowpox vaccine (1796) — first vaccine ever |
| Diphtheria | Corynebacterium diphtheriae | Bacteria | Airborne | Throat / respiratory | DPT vaccine |
| Tetanus | Clostridium tetani | Bacteria | Wound infection (soil) | Motor neurons / muscles | DPT vaccine; ATS |
| Pneumonia | Streptococcus pneumoniae | Bacteria | Airborne | Lungs | PCV-13 vaccine; antibiotics |
| Ringworm | Trichophyton (fungus) | Fungi | Direct contact | Skin / scalp / nails | Antifungals (griseofulvin) |
| Athlete's foot | Trichophyton (fungus) | Fungi | Contact / damp surfaces | Feet (skin between toes) | Antifungal creams |
| Ascariasis | Ascaris lumbricoides (roundworm) | Parasite | Contaminated food/soil | Intestines | Albendazole/mebendazole |
PLANT BIOLOGY
Plants are autotrophs — they produce their own food via photosynthesis. Chlorophyll (found in chloroplasts) captures light energy. Leaves are the primary site of photosynthesis, although stems and other green parts can also photosynthesize. Plants also respire (like animals), transpire (lose water vapour), and reproduce via pollination.
| Concept | Detail | Key Facts / Examples |
|---|---|---|
| Photosynthesis | 6CO₂ + 6H₂O + light energy → C₆H₁₂O₆ + 6O₂ | Chlorophyll absorbs red & blue light; reflects green (so leaves look green). Occurs in chloroplasts. |
| C3 Plants | First product is 3-carbon compound (3-PGA) | Rice, wheat, soybean, sunflower — common cool-climate crops |
| C4 Plants | First product is 4-carbon compound; more efficient at high temp | Sugarcane, maize (corn), sorghum — tropical crops; higher yield |
| Respiration (Plants) | Glucose + O₂ → CO₂ + H₂O + energy (aerobic) | Opposite of photosynthesis; occurs in all living cells 24/7 |
| Transpiration | Evaporation of water from leaves through stomata | Drives water uptake; stomata close at night; cacti have reduced stomata |
| Pollination | Transfer of pollen from anther to stigma | Self-pollination (same flower/plant) vs Cross-pollination (different plant) |
| Pollination agents | Wind (anemophily), Water (hydrophily), Insects (entomophily), Birds (ornithophily) | Wind-pollinated flowers are small, odourless; insect-pollinated are bright, scented |
| Osmosis | Movement of water from high to low concentration through semi-permeable membrane | Root hair cells absorb water by osmosis from soil |
| Phototropism | Plant growth towards light | Stem: positive phototropism; Root: negative |
| Geotropism | Plant growth in response to gravity | Root: positive geotropism (grows down); Stem: negative |
| Auxins | Plant hormone that promotes cell elongation | Controls phototropism and gravitropism |
ECOLOGY & ENVIRONMENT
Ecology (term coined by Reiter) studies the relationships between organisms and their environment. The term was popularized by Ernst Haeckel. Ecological organization: individual → population → community → ecosystem → biome → biosphere. Energy flows through ecosystems in one direction (sun → producers → consumers → decomposers) — only ~10% is transferred to the next trophic level (10% law by Lindemann).
A simple food chain: Grass → Grasshopper → Frog → Snake → Eagle. Food webs are interconnected food chains. The trophic level that has the most energy is always the producers (plants). Ecological pyramids (of number, biomass, energy) show relationships between trophic levels. Pyramid of energy is always upright (energy decreases up the chain).
| Term | Meaning | Example |
|---|---|---|
| Ecosystem | Community of organisms + their non-living environment | Forest, pond, coral reef |
| Biome | Large natural zone with characteristic climate and flora/fauna | Desert, tropical rainforest, tundra |
| Food chain | Linear sequence of who eats whom | Grass → Deer → Tiger |
| Food web | Multiple interconnected food chains | Grassland with many prey-predator links |
| Producers (Autotrophs) | Organisms that make their own food | Plants, algae, cyanobacteria |
| Consumers (Heterotrophs) | Organisms that eat others | Herbivores (1°), Carnivores (2°/3°), Omnivores |
| Decomposers | Break down dead matter; recycle nutrients | Bacteria, fungi (Rhizopus, Aspergillus) |
| Trophic level | Position in food chain | Plants = T1, herbivore = T2, carnivore = T3 |
| 10% Law (Lindemann) | Only 10% energy transferred to next trophic level | 100 J in plants → 10 J in herbivore → 1 J in carnivore |
| Biomagnification | Toxin concentration increases up the food chain | DDT: highest in eagles (top predator) |
| Biodiversity | Variety of life in an area (species, genetic, ecosystem) | Amazon rainforest has highest biodiversity |
| Habitat | Natural home environment of an organism | Pond for fish; forest for tiger |
| Niche | Role/function of organism in its ecosystem | Eagle = apex predator in forest niche |
| Symbiosis | Close interaction between two species | Lichens (fungi + algae); Rhizobium in legume roots (nitrogen fixation) |
| Pyramid of energy | Always upright (energy decreases upward) | Most energy at producer level |
| Pyramid of biomass | Upright in grassland/forest; inverted in pond | Pond: small phytoplankton support large zooplankton biomass |
| Acid rain | Rain with pH < 5.6 due to SO₂ and NO₂ | Damages forests, corrodes marble (Taj Mahal effect) |
| Ozone depletion | CFCs release Cl atoms → destroy O₃ | UV-B radiation → skin cancer, eye damage |
| Biomass energy | Energy from organic matter (plant/animal waste) | Biogas (methane from cow dung), ethanol from sugarcane |
VITAMINS — COMPLETE GUIDE
Vitamins are organic compounds our body needs in tiny amounts but cannot make on its own (except Vitamin D from sunlight and Vitamin K from gut bacteria). They're split into two groups: fat-soluble (A, D, E, K — stored in body fat; excess is dangerous) and water-soluble (B-complex and C — excess flushed out in urine; need regular intake). Deficiency of each vitamin causes a specific disease — this is a direct SSC question type almost every paper.
Fat-Soluble Vitamins (A, D, E, K)
Fat-soluble vitamins are absorbed along with fats in food and stored in the liver and fatty tissues. Since the body stores them, you don't need them daily — but too much can build up to toxic levels. Memory hook: A-D-E-K (think of "ADEK the fat kid who stores everything").
| Vitamin | Chemical Name | Rich Food Sources | Function | Deficiency Disease |
|---|---|---|---|---|
| A | Retinol | Fish liver oil, carrots, spinach, dairy, egg yolk | Maintains healthy eyes (rhodopsin in rod cells), skin, and immune function | Night blindness (Nyctalopia); dry skin; Xerophthalmia (dry eyes) |
| D | Calciferol | Fish oils, egg yolk, butter; made by skin in sunlight | Absorbs calcium from intestines; builds strong bones and teeth | Rickets in children (soft/bent bones); Osteomalacia in adults (painful soft bones) |
| E | Tocopherol | Vegetable oils, nuts, seeds, leafy greens | Antioxidant; forms red blood cells; affects muscles and reproductive system | Mild anaemia; muscle weakness; sterility (rare in humans) |
| K | Phylloquinone | Dark green leafy vegetables (spinach, fenugreek); also made by gut bacteria | Blood clotting — needed to make prothrombin (clotting factor) | Delayed/excessive bleeding; haemorrhage in newborns (no gut bacteria yet) |
Water-Soluble Vitamins (B-complex & C)
Water-soluble vitamins dissolve in water and aren't stored — excess is excreted in urine. This means you need them regularly from food. The B-complex group has many members (B1, B2, B3, B5, B6, B9, B12) — each with a different role and deficiency disease. Vitamin C (ascorbic acid) is famous for scurvy prevention (the disease that killed sailors who had no fresh fruit for months).
| Vitamin | Chemical Name | Key Source | Deficiency Disease / Effect |
|---|---|---|---|
| B₁ | Thiamine | Yeast, cereals, nuts, pork | Beriberi — nervous system damage, muscle weakness, swollen legs |
| B₂ | Riboflavin | Liver, milk, eggs, green vegetables | Cracked skin at corners of mouth; blurred vision; photophobia |
| B₃ | Niacin | Liver, yeast, whole cereals, beans | Pellagra — 3 Ds: Dermatitis, Diarrhoea, Dementia |
| B₅ | Pantothenic acid | Meat, eggs, whole grains | Pellagra-like symptoms; nerve damage; fatigue |
| B₆ | Pyridoxine | Meat, fish, eggs, cereals | Skin problems; nerve disorder; anaemia |
| B₉ | Folic acid | Liver, raw green vegetables, yeast | Anaemia; neural tube defects in foetus — CRITICAL during pregnancy |
| B₁₂ | Cyanocobalamin | Liver, milk, fish, eggs (NONE in plant foods) | Pernicious anaemia; nerve degeneration; memory issues |
| C | Ascorbic acid | Citrus fruits, amla (richest source), guava, berries, peppers | Scurvy — bleeding gums, poor wound healing, weakened immunity |
BLOOD GROUPS — DONATION & TRANSFUSION
Human blood comes in 4 main blood groups (A, B, AB, O) based on the antigens (protein markers) on red blood cells and the antibodies in blood plasma. If you receive blood with the wrong antigens, your antibodies attack the donor red cells — a life-threatening reaction. This is why blood group matching matters in transfusions. For SSC, memorise who can give blood to whom — especially O (universal donor) and AB (universal recipient).
| Blood Group | Antigen on RBCs | Antibodies in Plasma | Can Donate To | Can Receive From |
|---|---|---|---|---|
| O | None | Anti-A and Anti-B | O, A, B, AB (Universal Donor) | O only |
| A | A antigen | Anti-B | A and AB | O and A |
| B | B antigen | Anti-A | B and AB | O and B |
| AB | A and B antigens | None (no antibodies) | AB only | O, A, B, AB (Universal Recipient) |
BIOTECHNOLOGY — CLONING, IVF & GENETIC ENGINEERING
Biotechnology is biology put to practical use — using living organisms (bacteria, plants, animals) to make products or solve problems. It covers three big areas that SSC tests: Genetic Engineering (editing DNA), Test Tube Baby / IVF (fertilisation outside the body), and Cloning (creating a genetic copy). These sound sci-fi but each has real applications in medicine and agriculture.
| Technology | What It Is | Key Landmark | Application |
|---|---|---|---|
| Genetic Engineering | Inserting a foreign gene fragment into another organism's DNA to give it new traits | First GMO bacterium created 1973 (Boyer & Cohen) | Insulin production, pest-resistant crops, gene therapy |
| Gene Therapy | Inserting correct genes into patients' cells to treat hereditary diseases | First approved 1990 (USA, for ADA-SCID) | Treating genetic diseases like haemophilia, cystic fibrosis |
| IVF (In Vitro Fertilisation) / Test Tube Baby | Egg and sperm fertilised outside the body in a lab (in vitro = in glass); embryo implanted in uterus | World's 1st test tube baby: Louise Joy Brown, UK, 25 July 1978; India's 1st: Harsha, Mumbai, 6 Aug 1986 | Helps infertile couples have children |
| Cloning | Creating a genetically identical copy of an organism from a single cell (asexual reproduction) | Dolly the sheep — 1st mammal clone; by Dr Ian Wilmut, UK, 1996 | Organ cloning (research stage); conservation of endangered species |
| Bt Crops (GMO crops) | Crops with Bacillus thuringiensis (Bt) bacteria gene inserted — produces insect-killing toxin naturally | Bt-cotton was India's first approved GM crop (2002); also Bt-corn, golden rice | Reduces pesticide use; increases yield; golden rice provides Vitamin A |
BRANCHES OF BIOLOGY & MEDICAL DISCOVERIES
SSC often asks "What is the study of X called?" or "Who discovered Y?" These are pure memory questions — 1 mark each, easily scored. Learn the -ology words and the key discoverers.
| Branch | What It Studies |
|---|---|
| Anatomy | Structure of the human body (internal organs) |
| Physiology | Functions of body organs and systems |
| Cytology | Cells (structure and function) |
| Genetics | Heredity and variation (how traits pass from parent to child) |
| Ecology | Relationships between organisms and their environment |
| Taxonomy | Classification of living organisms |
| Virology | Viruses — their structure and diseases |
| Pathology | Disease-causing organisms and mechanisms |
| Cardiology | Heart and cardiovascular system |
| Nephrology | Kidneys and urinary system |
| Dermatology | Skin and skin diseases |
| Ornithology | Birds |
| Entomology | Insects |
| Mycology | Fungi |
| Phycology | Algae |
| Serology / Sericulture | Silk industry (silk moth culture) |
| Apiculture | Bee keeping / honey industry |
| Pisciculture | Fish farming |
| Horticulture | Garden plants, fruits, vegetables |
| Anthropology | Apes and humans — evolution and culture |
| Discovery | Discoverer | Year | Country |
|---|---|---|---|
| Antibiotic (Penicillin) | Alexander Fleming | 1928 | Scotland |
| Antiseptic (surgical) | Joseph Lister | 1867 | Scotland |
| Blood circulation | William Harvey | 1628 | Britain |
| Blood groups (ABO) | Karl Landsteiner | 1901 | Austria |
| X-rays | WC Roentgen | 1895 | Germany |
| Stethoscope | René Laennec | 1819 | France |
| Cholera and TB germs | Robert Koch | 1883 | Germany |
| Electrocardiogram (ECG) | Willem Einthoven | 1903 | Netherlands |
| CT Scan | Godfrey Hounsfield | 1973 | England |
| Ultrasound imaging | Ian Donald | 1958 | Scotland/Ireland |
| EEG (Electroencephalogram) | Hans Berger | 1929 | Germany |
| Vaccination (smallpox) | Edward Jenner | 1796 | Britain |
| Rabies vaccine | Louis Pasteur | 1885 | France |
| Polio vaccine (injected) | Jonas Salk | 1955 | USA |
| Oral Polio Vaccine | Albert Sabin | 1961 | USA |
BIOLOGICAL RECORDS — SMALLEST & LARGEST
SSC loves asking "what is the largest/smallest X?" questions from biology. These are pure fact-recall — spend 10 minutes learning this table and you'll always get these marks.
| Category | Smallest | Largest |
|---|---|---|
| Cell in human body | Sperm cell (head ~5 μm) | Neuron / Nerve cell (up to 1 m long) |
| Bone in human body | Stapes (stirrup bone in ear) | Femur (thigh bone) |
| Muscle in human body | Stapedius (middle ear muscle) | Gluteus maximus (buttock) |
| Endocrine gland | Pituitary gland ('master gland') | Thyroid gland |
| Mammal (land) | Shrew (Suncus etruscus) | African elephant |
| Mammal (on Earth) | Shrew | Blue whale |
| Bird | Humming bird (Cuba) | Ostrich |
| Flower (global) | Wolffia microscopica (angiosperm) | Rafflesia (parasitic plant — up to 1 m diameter) |
| Flower in India | — | Sapria |
| Egg / Cell | — | Ostrich egg (largest single cell) |
| Blood vessel (vein) | Capillaries | Inferior vena cava |
| Blood vessel (artery) | Arterioles | Abdominal aorta |
| Virus | Foot and mouth disease virus | Parrot fever virus (Psittacosis virus) |
| Tallest angiosperm (flowering plant) | — | Eucalyptus |
| Tallest gymnosperm | — | Sequoia sempervirens (Coastal Redwood) |
| Coral reef | — | Great Barrier Reef (Australia) |
QUICK-FIRE FACTS (SSC Favourites)
| Question | Answer |
|---|---|
| Who discovered penicillin? | Alexander Fleming (1928) from Penicillium notatum |
| Who discovered blood circulation? | William Harvey (1628) |
| Who coined 'Cell'? | Robert Hooke (1665) — observed cork cells under microscope |
| Cell theory proposed by | Schleiden & Schwann (1838); Virchow added 'cells from cells' |
| Father of Genetics | Gregor Mendel |
| Father of Biology / Zoology | Aristotle |
| Father of Botany | Theophrastus |
| Father of Taxonomy | Carolus Linnaeus |
| Father of Medicine | Hippocrates |
| Father of Microbiology | Antonie van Leeuwenhoek (invented microscope) |
| Father of Immunology | Louis Pasteur |
| Smallest bone in body | Stapes (ear) |
| Largest bone in body | Femur (thigh) |
| Largest muscle | Gluteus maximus |
| Smallest muscle | Stapedius (ear) |
| Smallest endocrine gland | Pituitary gland |
| Longest cell in body | Neuron (nerve cell) |
| Largest cell in body | Ovum (egg cell) / Ostrich egg |
| Universal blood donor | Blood group O (Rh–) |
| Universal blood recipient | Blood group AB (Rh+) |
| RBC lifespan | 120 days (about 4 months) |
| Platelet lifespan | 8–10 days |
| WBC that fights bacteria | Neutrophils (65%; phagocytic) |
| WBC called 'policeman of blood' | Monocytes |
| Normal blood pH | 7.35–7.45 (slightly alkaline) |
| Normal blood pressure | 120/80 mmHg |
| Pacemaker of heart | SA node (sino-atrial node) in right atrium |
| Number of chromosomes in humans | 46 (23 pairs) |
| DNA double helix discovered by | Watson & Crick (1953) |
| First cloned mammal | Dolly the sheep (Ian Wilmut, 1996) |
| First vaccine ever | Smallpox vaccine by Edward Jenner (1796) |
| Who discovered X-rays? | Wilhelm Conrad Röntgen (1895) |
| Malaria caused by | Plasmodium (protozoan parasite); vector = female Anopheles mosquito |
| Dengue caused by | Flavivirus; vector = Aedes aegypti mosquito |
| TB caused by | Mycobacterium tuberculosis; vaccine = BCG |
| AIDS caused by | HIV (retrovirus); attacks CD4 T-helper cells |
| Plague caused by | Yersinia pestis (bacteria); vector = rat fleas |
| Photosynthesis equation | 6CO₂ + 6H₂O + light → C₆H₁₂O₆ + 6O₂ |
| Which gas is released in photosynthesis? | Oxygen (O₂) |
| Which gas is absorbed in photosynthesis? | Carbon dioxide (CO₂) |
| Chlorophyll absorbs which light? | Red and blue light (reflects green — hence plants look green) |
| 10% Law in ecology by | Lindemann — only 10% energy passes to next trophic level |
| Biomagnification example | DDT concentrates in apex predators (eagles, humans) |
| Acid rain components | H₂SO₄ (sulphuric acid) + HNO₃ (nitric acid) |
| Ozone depletion by | CFCs (chlorofluorocarbons) releasing chlorine atoms |
COMMON EXAM TRAPS
- 'Dengue spreads via Anopheles mosquito' — WRONG. Dengue = Aedes aegypti. Malaria = Anopheles (female only).
- 'Digestion starts in the stomach' — WRONG. It starts in the mouth (salivary amylase breaks down starch).
- 'AB blood group is the universal donor' — WRONG. AB is the universal RECIPIENT. O is the universal donor.
- 'Viruses are treated with antibiotics' — WRONG. Antibiotics kill bacteria only. Viral infections need antivirals or vaccines.
- 'The pituitary is the largest endocrine gland' — WRONG. Pituitary is the smallest endocrine gland; thyroid is the largest.
- 'Infants have 206 bones' — WRONG. Infants have ~300 bones; adults have 206 (many bones fuse during growth).
- 'Robert Koch invented the rabies vaccine' — WRONG. Koch discovered the cholera/TB bacterium. Rabies vaccine = Louis Pasteur (1885).
- 'Mendel experimented on fruit flies' — WRONG. Mendel used pea plants (Pisum sativum). Fruit flies (Drosophila) were used by T.H. Morgan for chromosome mapping.
- 'Photosynthesis occurs only in leaves' — WRONG. It occurs in all green parts of plants (stems, unripe fruits, etc.).
- 'DNA was discovered by Watson & Crick' — WRONG. DNA was discovered earlier by Friedrich Miescher (1869). Watson & Crick discovered the double-helix structure (1953).
- 'Sex of a child is determined by the mother' — WRONG. Sex is determined by the father's sperm chromosome (X → daughter; Y → son).
- 'Insulin is secreted by the thyroid gland' — WRONG. Insulin is secreted by beta cells of the Islets of Langerhans in the pancreas.
- 'Vitamin D is obtained only from food' — WRONG. Vitamin D is also synthesised by skin under sunlight (UV-B radiation converts 7-dehydrocholesterol → Vitamin D₃).
- 'All mosquitoes spread malaria' — WRONG. Only the female Anopheles mosquito spreads malaria (males feed on nectar, not blood).
- 'Pyramid of biomass is always upright' — WRONG. Pyramid of biomass is inverted in a pond ecosystem (phytoplankton have less biomass but support larger zooplankton). Pyramid of energy is always upright.

